Quantum Blue® fCAL

The Quantum Blue® fCAL product line offers lateral flow-based quantitative calprotectin testing within 15 minutes. BÜHLMANN offers tests covering 2 different ranges suitable for diagnosis and therapy follow-up of IBD patients. Several independent clinical studies have proven the reliability and diagnostic accuracy of the Quantum Blue® fCAL assays. Check out our calprotectin overview page for more information.


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Calprotectin – Differentiating IBD from non-inflammatory Diseases

Inflammatory Bowel Disease (IBD) affects approximately 2 million people in Europe and shows increasing prevalence all over the world. Crohn’s Disease (CD) and Ulcerative Colitis (UC) are incurable serious chronic diseases of the intestinal tract. Symptoms of IBD strongly resemble those of non-inflammatory diseases such as the irritable bowel syndrome (IBS), polyps or even gastrointestinal infections. Calprotectin has proven itself as a very good surrogate marker in the diagnosis of IBD and helps therefore to reliably select patients for further invasive diagnostic procedures. It is assumed that IBS affects over 30 million people in Europe and results in over 2 million yearly visits to physicians. Twenty to thirty percent of all visits to gastroenterologists are due to symptoms of IBS. Calprotectin is therefore the ideal diagnostic tool to discriminate between inflammatory and non-inflammatory conditions in the gastrointestinal tract.


Calprotectin – Monitoring IBD Disease Activity

The clinical course of most patients with IBD is marked by periods of remission with intermittent relapses characterized by increased intestinal inflammation. Numerous published studies by Tibble et al. and others, have studied the levels of calprotectin in patients during the course of the disease. The results show that calprotectin is a good predictor of relapse in patients with IBD, thus giving clinicians an effective tool to adapt the patients treatment accordingly and to ease the relapse severity.


Quantum Blue® fCAL Product Information

Test Quantum Blue® fCAL Extended Quantum Blue® fCAL High Range
Order Code LF-CALE25 LF-CHR25
Time to Result 12 min (approx.) 15 min (approx.)
Sample Type Feces Feces
Standard Range 30 -1000 µg/g 100 -1800 µg/g
Sensitivity <30 µg/g <100 µg/g
Lot-specific Control Set
included in the kit
included in the kit
Reader Compatibility
Quantum Blue® Reader 3rd generation /
Quantum Blue® Reader 2nd generation
Quantum Blue® Reader 3rd generation /
Quantum Blue® Reader 2nd generation