The anti-SGPG Autoantibodies ELISA by BÜHLMANN is a semi-quantitative assay for determining IgM antibodies against SGPG.

Anti-SGPG antibodies have a wider spectrum than anti-MAG antibodies: some patients which are anti-SGPG positive are negative for anti-MAG antibodies. Therefore, combined testing enhances sensitivity.

The presence of anti-MAG/anti-SGPG antibodies is suggestive of a demyelinating neuropathy, whereas the presence of anti-SGPG antibodies alone seems to be more present in axonal non-demyelinating neuropathies, often of predominantly motor-type.

Uniqueness: The BÜHLMANN anti-SGPG Autoantibodies ELISA is the only CE-marked assay for IVD worldwide.

Accuracy: Pre-coated microtiter plates.

Specificity: The use of highly purified SGPG results in best likelihood to detect all positive patients.
Using microtiterplate with extremely low unspecific binding properties.
No blocking proteins thus reducing the chance for false positive samples.

Reproducibility: Pre-measured standards and two controls ensure low inter-assay variation.

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