BÜHLMANN sCAL® turbo
Serum Calprotectin is a powerful biomarker to detect the inflammatory status of a patient whether it is a classical autoimmune mediated Rheumatoid Arthritis (RA) or a rare auto-inflammatory disease like systemic juvenile idiopathic arthritis (sJIA) or Still’s disease (AOSD). Detection of elevated serum calprotectin levels support differential diagnosis, moreover calprotectin has been shown to help stratification and disease prediction to ensure optimal therapy and monitoring for patients.
The BÜHLMANN sCAL® turbo assay is your flexible and powerful tool to be applied on most clinical chemistry analyzers. The turbidimetric technology allows rapid and flexible random-access workflow and the automation capability offers high throughput options in the routine laboratory. Another major asset of the BÜHLMANN sCAL® turbo assay is the dramatically reduced hands-on allowing serum calprotectin result reporting within a very short time.
The wide measuring range covers the clinically relevant concentrations and includes automated re-run for extreme high-level concentrations without high dose hook effect up to >90 µg/mL. Last but not least very high precision and reproducibility is guaranteed with the BÜHLMANN sCAL® turbo method.
||BÜHLMANN sCAL® turbo
||Particle-enhanced turbidimetric immunoassay (PETIA)
Separated within 6 h after blood drawing
Stable for 15 days at room temperature
||2 reagents, last for ~100 tests (platform dependent)
||Stable for 90 days
||Stable for at least 30 days (platform dependent)
||0.3-15 µg/ml (extended range up to 225 µg/ml)
|Time to Result
||R1:R2 ratio = 1:3, analysis: kinetic
||Alinity; Architect* c-series
||AU Series: AU480, AU680, AU5800, DxC700AU
||cobas c501/c502, c303*, c503**
||Atellica CH 930**
|The Binding Site
*validation ongoing; **validation planned; contact firstname.lastname@example.org for information