Buehlmann


The first commercially available Vasopressin RIA


Vasopressin

Anti-diuretic hormone (ADH), or [Arg8]-Vasopressin (AVP), is a peptide hormone produced by the hypothalamus and stored in the posterior part of pituitary gland. ADH acts on kidneys, concentrating urine by promoting the re-absorption of water from the cortical collecting duct.
Decreased ADH release leads to diabetes insipidus, a condition featuring hypernatremia (increased blood sodium content), pollyuria (excess urine production) and thirst.

testRaised ADH levels (Syndrome of Inappropriate Antidiuretic Hormone or SIADH), and the resulting hyponatremia, occurs in diseases of the brain and lung. In the perioperative period, the effects of surgical stress and some commonly used medications (e.g. opiates, syntocinon, anti-emetics) lead to a similar state of excess ADH secretion. This may cause mild hyponatremia for several days.
Vasopressin direct RIA
Role in disease:
• Decreased ADH leads to diabetes insipidus, a condition featuring hypernatremia (increased blood sodium content), polyuria (excess urine production) and thirst.
• Raised ADH (syndrome of inappropriate antidiuretic hormone, SIADH) and resultant hyponatremia occurs in brain diseases and conditions of the lungs. In the peri-operative period, the effects of surgical stress and some commonly used medications lead to a similar state of excess ADH secretion. This may cause mild hyponatremia for several days.

Advantages of the BUHLMANN VASOPRESSIN RIA:

Sensitivity:

1.25 pg/ml                                                                                          

Specificity:

<0.001% cross-reactivity with Oxytocin

Reproducibility:

pre-measured standards and two controls

Product Information

Vasopressin Vasopressin Direct

Method

125I-RIA 125I-RIA

Time to results

48 h 48 h

Sample Type

1 ml EDTA plasma & urine 0.8 ml EDTA plasma

Standard range

0.63-80  pg/ml 1.25-80  pg/ml

Sensitivity

0.4 pg/ml 0.75 pg/ml

Order Code

RK- AR1 100 tests RK- VPD 100 tests
CE CE

* Multilingual document [EN, DE, FR, IT, ES]
DOWNLOADS

Instruction
for use* Vasopressin

Instruction
for use* Vasopressin direct

Technical information

Labelling schedule

English

[PDF 0.4MB] [PDF 0.3MB] [PDF 0.7MB] 2012 [PDF 150 KB]
 

Contact

BÜHLMANN Laboratories AG
Baselstr. 55
CH-4124 Schönenbuch
Switzerland
Fon: +41 61 487 12 12
Fax: +41 61 487 12 34
info@buhlmannlabs.ch

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